产品货号：
Z30224
中文名称：
IGF2R抗体
英文名称：
Anti-IGF2R Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IGF2R Antibody |
| 指标别名 | CD222;CI Man 6 P receptor;CI MPR;CIMPR;IGF II receptor;IGF2R;IGF2R-Specific;Lysosome Marker;M6P R;M6P/IGF2 receptor;M6P/IGF2R;M6PR;MPR 300;MPR1;MPRI |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | IGF2R |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent)(2475-2491aa TKLVSFHDDSDEDLLHI),different from the related rat and mouse sequences by one amino acid. |
| 实际分子量 | 274KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Insulin-like growth factor 2 receptor,also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene.This gene is mapped to 6q25.3.This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate,although the binding sites for either are located on different segments of the receptor.This receptor functions in the intracellular trafficking of lysosomal enzymes,the activation of transforming growth factor beta,and the degradation of insulin-like growth factor 2.While the related mouse gene shows exclusive expression from the maternal allele,imprinting of the human gene appears to be polymorphic,with only a minority of individuals showing expression from the maternal allele. |
| Uniprot ID | P11717 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | insulin-like growth factor 2 receptor |
| 蛋白名全称 | Cation-independent mannose-6-phosphate receptor |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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